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Systematic detection of m(6)A-modified transcripts at single-molecule and single-cell resolution

Epigenetic modifications control the stability and translation of mRNA molecules. Here, we present a microscopy-based platform for quantifying modified RNA molecules and for relating the modification patterns to single-cell phenotypes. We directly capture mRNAs from cell lysates on oligo-dT-coated c...

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Detalles Bibliográficos
Autores principales:	Kim, Kyung Lock, van Galen, Peter, Hovestadt, Volker, Rahme, Gilbert J., Andreishcheva, Ekaterina N., Shinde, Abhijeet, Gaskell, Elizabeth, Jones, Daniel R., Shema, Efrat, Bernstein, Bradley E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562683/ https://www.ncbi.nlm.nih.gov/pubmed/34734208 http://dx.doi.org/10.1016/j.crmeth.2021.100061

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