Cargando…
Perfluoroalkyl Carboxylic Acids Interact with the Human Bile Acid Transporter NTCP
Na(+)/taurocholate cotransporting polypeptide (NTCP) is important for the enterohepatic circulation of bile acids, which has been suggested to contribute to the long serum elimination half-lives of perfluoroalkyl substances in humans. We demonstrated that some perfluoroalkyl sulfonates are transport...
Autores principales: | Ruggiero, Melissa J., Miller, Haley, Idowu, Jessica Y., Zitzow, Jeremiah D., Chang, Shu-Ching, Hagenbuch, Bruno |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562773/ https://www.ncbi.nlm.nih.gov/pubmed/34738093 http://dx.doi.org/10.3390/livers1040017 |
Ejemplares similares
-
Free Cholesterol Affects the Function and Localization of Human Na(+)/Taurocholate Cotransporting Polypeptide (NTCP) and Organic Cation Transporter 1 (OCT1)
por: Idowu, Jessica Y., et al.
Publicado: (2022) -
Structural insights into the HBV receptor and bile acid transporter NTCP
por: Park, Jae-Hyun, et al.
Publicado: (2022) -
NTCP Deficiency Affects the Levels of Circulating Bile Acids and Induces Osteoporosis
por: Yang, Fangji, et al.
Publicado: (2022) -
Structural Plasticity Is a Feature of Rheostat Positions in the Human Na(+)/Taurocholate Cotransporting Polypeptide (NTCP)
por: Ruggiero, Melissa J., et al.
Publicado: (2022) -
A clinically relevant polymorphism in the Na(+)/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position
por: Ruggiero, Melissa J., et al.
Publicado: (2020)