Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties

BACKGROUND: The transcription factor NF-κB drives neoplastic progression of many cancers including primary brain tumors (glioblastoma [GBM]). Precise therapeutic modulation of NF-κB activity can suppress central oncogenic signaling pathways in GBM, but clinically applicable compounds to achieve this...

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Detalles Bibliográficos
Autores principales: Volmar, Marie N M, Cheng, Jiying, Alenezi, Haitham, Richter, Sven, Haug, Alisha, Hassan, Zonera, Goldberg, Maria, Li, Yuping, Hou, Mengzhuo, Herold-Mende, Christel, Maire, Cecile L, Lamszus, Katrin, Flüh, Charlotte, Held-Feindt, Janka, Gargiulo, Gaetano, Topping, Geoffrey J, Schilling, Franz, Saur, Dieter, Schneider, Günter, Synowitz, Michael, Schick, Joel A, Kälin, Roland E, Glass, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563328/
https://www.ncbi.nlm.nih.gov/pubmed/33864076
http://dx.doi.org/10.1093/neuonc/noab095

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