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Role of the Polyol Pathway in Locomotor Recovery and Wallerian Degeneration after Spinal Cord Contusion Injury
Spinal cord contusion injury leads to Wallerian degeneration of axonal tracts, resulting in irreversible paralysis. Contusion injury causes perfusion loss by thrombosis and vasospasm, resulting in spinal cord ischemia. In several tissues, including heart and brain, ischemia activates polyol pathway...
Autores principales: | Zeman, Richard J., Wen, Xialing, Ouyang, Nengtai, Brown, Abraham M., Etlinger, Joseph D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563458/ https://www.ncbi.nlm.nih.gov/pubmed/34738094 http://dx.doi.org/10.1089/neur.2021.0018 |
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