Gain-of-Function Properties of a Dynamin 2 Mutant Implicated in Charcot-Marie-Tooth Disease

Mutations in the gene encoding dynamin 2 (DNM2), a GTPase that catalyzes membrane constriction and fission, are associated with two autosomal-dominant motor disorders, Charcot-Marie-Tooth disease (CMT) and centronuclear myopathy (CNM), which affect nerve and muscle, respectively. Many of these mutat...

Descripción completa

Detalles Bibliográficos
Autores principales: Tassin, Tara C., Barylko, Barbara, Hedde, Per Niklas, Chen, Yan, Binns, Derk D., James, Nicholas G., Mueller, Joachim D., Jameson, David M., Taussig, Ronald, Albanesi, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563704/
https://www.ncbi.nlm.nih.gov/pubmed/34744632
http://dx.doi.org/10.3389/fncel.2021.745940

Ejemplares similares

Ejemplares similares