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NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis

Primary cilia extending from mother centrioles are essential for vertebrate development and homeostasis maintenance. Centriolar coiled-coil protein 110 (CP110) has been reported to suppress ciliogenesis initiation by capping the distal ends of mother centrioles. However, the mechanism underlying the...

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Detalles Bibliográficos
Autores principales: Liu, Min, Zhang, Wen, Li, Min, Feng, Jiaxing, Kuang, Wenjun, Chen, Xiying, Yang, Feng, Sun, Qiang, Xu, Zhangqi, Hua, Jianfeng, Yang, Chunxia, Liu, Wei, Shu, Qiang, Yang, Yuehong, Zhou, Tianhua, Xie, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563757/
https://www.ncbi.nlm.nih.gov/pubmed/34480124
http://dx.doi.org/10.1038/s41422-021-00560-3