Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence

Cellular senescence is a stable cell cycle arrest that normal cells undergo after a finite number of divisions, in response to a variety of intrinsic and extrinsic stimuli. Although senescence is largely established and maintained by the p53/p21(WAF1/CIP1) and pRB/p16(INK4A) tumour suppressor pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumari, Ruchi, Hummerich, Holger, Shen, Xu, Fischer, Martin, Litovchick, Larisa, Mittnacht, Sibylle, DeCaprio, James A., Jat, Parmjit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563780/
https://www.ncbi.nlm.nih.gov/pubmed/34728711
http://dx.doi.org/10.1038/s41598-021-01012-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563780/
https://www.ncbi.nlm.nih.gov/pubmed/34728711
http://dx.doi.org/10.1038/s41598-021-01012-z

Ejemplares similares