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Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence
Cellular senescence is a stable cell cycle arrest that normal cells undergo after a finite number of divisions, in response to a variety of intrinsic and extrinsic stimuli. Although senescence is largely established and maintained by the p53/p21(WAF1/CIP1) and pRB/p16(INK4A) tumour suppressor pathwa...
Autores principales: | Kumari, Ruchi, Hummerich, Holger, Shen, Xu, Fischer, Martin, Litovchick, Larisa, Mittnacht, Sibylle, DeCaprio, James A., Jat, Parmjit S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563780/ https://www.ncbi.nlm.nih.gov/pubmed/34728711 http://dx.doi.org/10.1038/s41598-021-01012-z |
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