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YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human cancers. It thrives in a malnourished environment; however, little is known about the mechanisms by which PDAC cells actively promote aerobic glycolysis to maintain their metabolic needs. Gene Expression Omnibus (GEO) was used t...

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Detalles Bibliográficos
Autores principales: Hou, Yichao, Zhang, Qingwei, Pang, Wenjing, Hou, Lidan, Liang, Yu, Han, Xu, Luo, Xiaoyu, Wang, Ping, Zhang, Xintian, Li, Lei, Meng, Xiangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563797/
https://www.ncbi.nlm.nih.gov/pubmed/34021267
http://dx.doi.org/10.1038/s41418-021-00804-0