RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes

There remains a significant gap in our quantitative understanding of crosstalk between apoptosis and necroptosis pathways. By employing the SWATH-MS technique, we quantified absolute amounts of up to thousands of proteins in dynamic assembling/de-assembling of TNF signaling complexes. Combining SWAT...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Zhong, Chuan-Qi, Wu, Rui, Xu, Xiaozheng, Yang, Zhang-Hua, Cai, Shaowei, Wu, Xiurong, Chen, Xin, Yin, Zhiyong, He, Qingzu, Li, Dianjie, Xu, Fei, Yan, Yihua, Qi, Hong, Xie, Changchuan, Shuai, Jianwei, Han, Jiahuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563874/
https://www.ncbi.nlm.nih.gov/pubmed/33389663
http://dx.doi.org/10.1007/s13238-020-00810-x

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