The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry

The scope and variety of the metabolic intermediates from the mitochondrial tricarboxylic acid (TCA) cycle that are engaged in epigenetic regulation of the chromatin function in the nucleus raise an outstanding question about how timely and precise supply/consumption of these metabolites is achieved...

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Detalles Bibliográficos
Autores principales: Liu, Xujun, Si, Wenzhe, He, Lin, Yang, Jianguo, Peng, Yani, Ren, Jie, Liu, Xiaoping, Jin, Tong, Yu, Huajing, Zhang, Zihan, Cheng, Xiao, Zhang, Wenting, Xia, Lu, Huang, Yunchao, Wang, Yue, Liu, Shumeng, Shan, Lin, Zhang, Yu, Yang, Xiaohan, Li, Haixia, Liang, Jing, Sun, Luyang, Shang, Yongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563883/
https://www.ncbi.nlm.nih.gov/pubmed/34728602
http://dx.doi.org/10.1038/s41392-021-00774-2

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