Molecular programs of fibrotic change in aging human lung

Lung fibrosis is increasingly detected with aging and has been associated with poor outcomes in acute lung injury or infection. However, the molecular programs driving this pro-fibrotic evolution are unclear. Here we profile distal lung samples from healthy human donors across the lifespan. Gene exp...

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Detalles Bibliográficos
Autores principales: Lee, Seoyeon, Islam, Mohammad Naimul, Boostanpour, Kaveh, Aran, Dvir, Jin, Guangchun, Christenson, Stephanie, Matthay, Michael A., Eckalbar, Walter L., DePianto, Daryle J., Arron, Joseph R., Magee, Liam, Bhattacharya, Sunita, Matsumoto, Rei, Kubota, Masaru, Farber, Donna L., Bhattacharya, Jahar, Wolters, Paul J., Bhattacharya, Mallar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563941/
https://www.ncbi.nlm.nih.gov/pubmed/34728633
http://dx.doi.org/10.1038/s41467-021-26603-2

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