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Charting differentially methylated regions in cancer with Rocker-meth

Differentially DNA methylated regions (DMRs) inform on the role of epigenetic changes in cancer. We present Rocker-meth, a new computational method exploiting a heterogeneous hidden Markov model to detect DMRs across multiple experimental platforms. Through an extensive comparative study, we first d...

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Detalles Bibliográficos
Autores principales:	Benelli, Matteo, Franceschini, Gian Marco, Magi, Alberto, Romagnoli, Dario, Biagioni, Chiara, Migliaccio, Ilenia, Malorni, Luca, Demichelis, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563962/ https://www.ncbi.nlm.nih.gov/pubmed/34728774 http://dx.doi.org/10.1038/s42003-021-02761-3

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