Idiotype vaccines produced with a non-cytopathic alphavirus self-amplifying RNA vector induce antitumor responses in a murine model of B-cell lymphoma

A promising therapy for patients with B-cell lymphoma is based on vaccination with idiotype monoclonal antibodies (mAbs). Since idiotypes are different in each tumor, a personalized vaccine has to be produced for each patient. Expression of immunoglobulins with appropriate post-translational modific...

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Detalles Bibliográficos
Autores principales: Casales, Erkuden, Martisova, Eva, Villanueva, Helena, de Cerio, Ascensión López Díaz, Inoges, Susana, Silva-Pilipich, Noelia, Ballesteros-Briones, María Cristina, Aranda, Alejandro, Bezunartea, Jaione, Bendandi, Maurizio, Pastor, Fernando, Smerdou, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563967/
https://www.ncbi.nlm.nih.gov/pubmed/34728659
http://dx.doi.org/10.1038/s41598-021-00787-5

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