Cargando…

Eupafolin induces apoptosis and autophagy of breast cancer cells through PI3K/AKT, MAPKs and NF-κB signaling pathways

Eupafolin is a flavonoid that can be extracted from common sage. Previous studies have reported that Eupafolin has antioxidant, anti-inflammatory and anti-tumor properties. However, no studies have investigated the role of Eupafolin in breast cancer. Herein, we investigated the effect of Eupafolin o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Jiahui, Ding, Yu, Liu, Xinmiao, Liu, Qing, Lu, Yiran, He, Song, Yuan, Bao, Zhang, Jiabao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563970/ https://www.ncbi.nlm.nih.gov/pubmed/34728712 http://dx.doi.org/10.1038/s41598-021-00945-9

Ejemplares similares

Retraction Note: Eupafolin induces apoptosis and autophagy of breast cancer cells through PI3K/AKT, MAPKs and NF-κB signaling pathways
por: Wei, Jiahui, et al.
Publicado: (2021)

Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway
por: Wei, Jiahui, et al.
Publicado: (2021)

Eupafolin ameliorates lipopolysaccharide-induced cardiomyocyte autophagy via PI3K/AKT/mTOR signaling pathway
por: Gao, Yan, et al.
Publicado: (2019)

Eupafolin alleviates cerebral ischemia/reperfusion injury in rats via blocking the TLR4/NF-κB signaling pathway
por: Chen, Xingwang, et al.
Publicado: (2020)

Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways
por: Lu, Rui, et al.
Publicado: (2023)

Zearalenone Induces Apoptosis and Cytoprotective Autophagy in Chicken Granulosa Cells by PI3K-AKT-mTOR and MAPK Signaling Pathways
por: Zhu, Yifeng, et al.
Publicado: (2021)

Isorhamnetin Induces Melanoma Cell Apoptosis via the PI3K/Akt and NF-κB Pathways
por: Duan, Ran, et al.
Publicado: (2020)

Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway
por: Liu, Jiayu, et al.
Publicado: (2019)

Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma
por: Yu, Xiying, et al.
Publicado: (2020)

PLCA8 suppresses breast cancer apoptosis by activating the PI3k/AKT/NF‐κB pathway
por: Mao, Misha, et al.
Publicado: (2019)

Mycobacterial Heparin-binding Hemagglutinin Antigen Activates Inflammatory Responses through PI3-K/Akt, NF-κB, and MAPK Pathways
por: Kim, Ki-Hye, et al.
Publicado: (2011)

Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells
por: Shari, Khawlah, et al.
Publicado: (2023)

Mechanical Stimulation Protects Against Chondrocyte Pyroptosis Through Irisin-Induced Suppression of PI3K/Akt/NF-κB Signal Pathway in Osteoarthritis
por: Jia, Shuangshuo, et al.
Publicado: (2022)

Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFκB, and Hypoxia)
por: Tang, Yin-Quan, et al.
Publicado: (2013)

Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma
por: Wang, Rong, et al.
Publicado: (2018)

Eriodictyol Inhibits Proliferation, Metastasis and Induces Apoptosis of Glioma Cells via PI3K/Akt/NF-κB Signaling Pathway
por: Li, Wenjun, et al.
Publicado: (2020)

Naproxen-Derived New Compound Inhibits the NF-κB, MAPK and PI3K/Akt Signaling Pathways Synergistically with Resveratrol in RAW264.7 Cells
por: Ou, Yi, et al.
Publicado: (2023)

Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF-κB and MAPK signalling transduction through integrin αVβ3
por: Wan, Junlai, et al.
Publicado: (2023)

Boeravinone B, a natural rotenoid, inhibits osteoclast differentiation through modulating NF-κB, MAPK and PI3K/Akt signaling pathways
por: Piao, Xianyu, et al.
Publicado: (2023)

Triple Cross‐linked Dynamic Responsive Hydrogel Loaded with Selenium Nanoparticles for Modulating the Inflammatory Microenvironment via PI3K/Akt/NF‐κB and MAPK Signaling Pathways
por: Wang, Shuangqing, et al.
Publicado: (2023)

Bovine ephemeral fever virus triggers autophagy enhancing virus replication via upregulation of the Src/JNK/AP1 and PI3K/Akt/NF-κB pathways and suppression of the PI3K/Akt/mTOR pathway
por: Cheng, Ching-Yuan, et al.
Publicado: (2019)

IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAPK, and NF-kB Signaling in Rabbit Osteoarthritis
por: Hossain, Mohammad Amjad, et al.
Publicado: (2021)

Targeting the PI3K/AKT/mTOR/NFκB Axis in Ovarian Cancer
por: Ghoneum, Alia, et al.
Publicado: (2020)

Eupafolin Exhibits Potent Anti-Angiogenic and Antitumor Activity in Hepatocellular Carcinoma
por: Jiang, Honglei, et al.
Publicado: (2017)

Polydatin inhibits mast cell-mediated allergic inflammation by targeting PI3K/Akt, MAPK, NF-κB and Nrf2/HO-1 pathways
por: Ye, Jing, et al.
Publicado: (2017)

Cystic fibrosis transmembrane conductance regulator prevents ischemia/reperfusion induced intestinal apoptosis via inhibiting PI3K/AKT/NF-κB pathway
por: Dong, Zhi-Wei, et al.
Publicado: (2022)

The Chlamydia psittaci Inclusion Membrane Protein 0556 Inhibits Human Neutrophils Apoptosis Through PI3K/AKT and NF-κB Signaling Pathways
por: He, Zhangping, et al.
Publicado: (2021)

Effect of Compound Chuanxiong Capsule on Inflammatory Reaction and PI3K/Akt/NF-κB Signaling Pathway in Atherosclerosis
por: Kang, Qunfu, et al.
Publicado: (2015)

Blocks to thyroid cancer cell apoptosis can be overcome by inhibition of the MAPK and PI3K/AKT pathways
por: Gunda, V, et al.
Publicado: (2014)

The Neuroprotection of Liraglutide Against Ischaemia-induced Apoptosis through the Activation of the PI3K/AKT and MAPK Pathways
por: Zhu, Huili, et al.
Publicado: (2016)

Emodin Promotes Apoptosis of Human Endometrial Cancer Through Regulating the MAPK and PI3K/ AKT Pathways
por: Jiang, Jun, et al.
Publicado: (2019)

Azoxystrobin induces apoptosis via PI3K/AKT and MAPK signal pathways in oral leukoplakia progression
por: Li, Lingyu, et al.
Publicado: (2022)

HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways
por: Nie, Xin, et al.
Publicado: (2022)

Regulation of Tumor Apoptosis of Poriae cutis-Derived Lanostane Triterpenes by AKT/PI3K and MAPK Signaling Pathways In Vitro
por: Yue, Shuai, et al.
Publicado: (2023)

Ursolic acid inhibits breast cancer growth by inhibiting proliferation, inducing autophagy and apoptosis, and suppressing inflammatory responses via the PI3K/AKT and NF-κB signaling pathways in vitro
por: Luo, Juan, et al.
Publicado: (2017)

Celecoxib regulates apoptosis and autophagy via the PI3K/Akt signaling pathway in SGC-7901 gastric cancer cells
por: LIU, MIN, et al.
Publicado: (2014)

Renshen Baidu Powder Attenuated Intestinal Inflammation and Apoptosis in Ulcerative Colitis Rats through the Inhibition of PI3K/AKT/NF-κB Signaling Pathway
por: Zhang, Peixu, et al.
Publicado: (2022)

Fengreqing Oral Liquid Exerts Anti-Inflammatory Effects by Promoting Apoptosis and Inhibiting PI3K/AKT and NF-κB Signaling Pathways
por: Rao, Zhili, et al.
Publicado: (2022)

Gas6 attenuates lipopolysaccharide-induced TNF-α expression and apoptosis in H9C2 cells through NF-κB and MAPK inhibition via the Axl/PI3K/Akt pathway
por: Li, Mengfang, et al.
Publicado: (2019)

Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway
por: Qin, Xiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_83blg9o4t6atfqqptjvqls9426