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The immune checkpoint VISTA exhibits high expression levels in human gliomas and associates with a poor prognosis

In human gliomas, anti-tumor T cell responses are inhibited through induction of local and systemic immunosuppression. Immune checkpoint blockade is proving to be a success in several types of cancers. However, many studies reported that the treatment of glioblastoma patients with anti-CTLA-4 or ant...

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Detalles Bibliográficos
Autores principales: Ghouzlani, Amina, Lakhdar, Abdelhakim, Rafii, Soumaya, Karkouri, Mehdi, Badou, Abdallah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563991/
https://www.ncbi.nlm.nih.gov/pubmed/34728682
http://dx.doi.org/10.1038/s41598-021-00835-0