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Reduced TREM2 activation in microglia of patients with Alzheimer's disease

Loss‐of‐function variants of triggering receptor expressed on myeloid cells 2 (TREM2) increase the risk of developing Alzheimer's disease (AD). The mechanism through which TREM2 contributes to the disease (TREM2 activation vs inactivation) is largely unknown. Here, we analyzed changes in a gene...

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Detalles Bibliográficos
Autores principales:	Okuzono, Yuumi, Sakuma, Hiroyuki, Miyakawa, Shuuichi, Ifuku, Masataka, Lee, Jonghun, Das, Debashree, Banerjee, Antara, Zhao, Yang, Yamamoto, Koji, Ando, Tatsuya, Sato, Shuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564098/ https://www.ncbi.nlm.nih.gov/pubmed/34523252 http://dx.doi.org/10.1002/2211-5463.13300

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