New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis

PURPOSE: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronar...

Descripción completa

Detalles Bibliográficos
Autores principales: Delanian, Sylvie, Awad, Sameh, de Gramont, Aimery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564468/
https://www.ncbi.nlm.nih.gov/pubmed/34754953
http://dx.doi.org/10.1016/j.ctro.2021.10.004
_version_ 1784593624681414656
author Delanian, Sylvie
Awad, Sameh
de Gramont, Aimery
author_facet Delanian, Sylvie
Awad, Sameh
de Gramont, Aimery
author_sort Delanian, Sylvie
collection PubMed
description PURPOSE: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronary tumor embolization followed 15 days later by cardiac radiotherapy (40.5 Gy/15 fractions). CASES: We report two cases of severe right cardiac metastasis with a history of abdominal cancer managed by this salvage treatment following residual cardiac mass after previous cardiac surgery. CONCLUSION: Both symptomatic patients improved progressively and were locally controlled for at least 1 year without toxicity.
format Online
Article
Text
id pubmed-8564468
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-85644682021-11-08 New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis Delanian, Sylvie Awad, Sameh de Gramont, Aimery Clin Transl Radiat Oncol Case Report PURPOSE: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronary tumor embolization followed 15 days later by cardiac radiotherapy (40.5 Gy/15 fractions). CASES: We report two cases of severe right cardiac metastasis with a history of abdominal cancer managed by this salvage treatment following residual cardiac mass after previous cardiac surgery. CONCLUSION: Both symptomatic patients improved progressively and were locally controlled for at least 1 year without toxicity. Elsevier 2021-10-24 /pmc/articles/PMC8564468/ /pubmed/34754953 http://dx.doi.org/10.1016/j.ctro.2021.10.004 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Delanian, Sylvie
Awad, Sameh
de Gramont, Aimery
New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_full New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_fullStr New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_full_unstemmed New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_short New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
title_sort new curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564468/
https://www.ncbi.nlm.nih.gov/pubmed/34754953
http://dx.doi.org/10.1016/j.ctro.2021.10.004
work_keys_str_mv AT delaniansylvie newcurativeapproachusingembolizationfollowedbymoderatedoseradiotherapyaftersurgicalfailureforlargerightheartmetastasis
AT awadsameh newcurativeapproachusingembolizationfollowedbymoderatedoseradiotherapyaftersurgicalfailureforlargerightheartmetastasis
AT degramontaimery newcurativeapproachusingembolizationfollowedbymoderatedoseradiotherapyaftersurgicalfailureforlargerightheartmetastasis

Ejemplares similares