The Omic Insights on Unfolding Saga of COVID-19

The year 2019 has seen an emergence of the novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease of 2019 (COVID-19). Since the onset of the pandemic, biological and interdisciplinary research is being carried out across the world at a rapid...

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Detalles Bibliográficos
Autores principales: Kaur, Arvinpreet, Chopra, Mehak, Bhushan, Mahak, Gupta, Sonal, Kumari P, Hima, Sivagurunathan, Narmadhaa, Shukla, Nidhi, Rajagopal, Shalini, Bhalothia, Purva, Sharma, Purnima, Naravula, Jalaja, Suravajhala, Renuka, Gupta, Ayam, Abbasi, Bilal Ahmed, Goswami, Prittam, Singh, Harpreet, Narang, Rahul, Polavarapu, Rathnagiri, Medicherla, Krishna Mohan, Valadi, Jayaraman, Kumar S, Anil, Chaubey, Gyaneshwer, Singh, Keshav K., Bandapalli, Obul Reddy, Kavi Kishor, Polavarapu Bilhan, Suravajhala, Prashanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564481/
https://www.ncbi.nlm.nih.gov/pubmed/34745097
http://dx.doi.org/10.3389/fimmu.2021.724914
Descripción
Sumario:The year 2019 has seen an emergence of the novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease of 2019 (COVID-19). Since the onset of the pandemic, biological and interdisciplinary research is being carried out across the world at a rapid pace to beat the pandemic. There is an increased need to comprehensively understand various aspects of the virus from detection to treatment options including drugs and vaccines for effective global management of the disease. In this review, we summarize the salient findings pertaining to SARS-CoV-2 biology, including symptoms, hosts, epidemiology, SARS-CoV-2 genome, and its emerging variants, viral diagnostics, host-pathogen interactions, alternative antiviral strategies and application of machine learning heuristics and artificial intelligence for effective management of COVID-19 and future pandemics.

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