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Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K(+) channels

ATP-sensitive K(+) (K(ATP)) channels couple cellular metabolism to electrical activity in many cell types. Wild-type K(ATP) channels are comprised of four pore forming (Kir6.x) and four regulatory (sulfonylurea receptor, SURx) subunits that each contain RKR endoplasmic reticulum retention sequences...

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Detalles Bibliográficos
Autores principales: Heitz, Benjamin A., Bränström, Robert, Yang, Wei, Huang, Yiding, Moede, Tilo, Leibiger, Ingo B., Leibiger, Barbara, Chen, Liu Qi, Yu, Jia, Yang, Shao-Nian, Larsson, Olof, Saavedra, S. Scott, Berggren, Per-Olof, Aspinwall, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564548/
https://www.ncbi.nlm.nih.gov/pubmed/34728728
http://dx.doi.org/10.1038/s41598-021-00988-y

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