Cotargeting of miR‐126‐3p and miR‐221‐3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling

Lung cancer is the leading cause of cancer‐related death worldwide. Late diagnosis and metastatic dissemination contribute to its low survival rate. Since microRNA (miRNA) deregulation triggers lung carcinogenesis, miRNAs might represent an interesting therapeutic tool for lung cancer management. We...

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Detalles Bibliográficos
Autores principales: Di Paolo, Daniela, Pontis, Francesca, Moro, Massimo, Centonze, Giovanni, Bertolini, Giulia, Milione, Massimo, Mensah, Mavis, Segale, Miriam, Petraroia, Ilaria, Borzi, Cristina, Suatoni, Paola, Brignole, Chiara, Perri, Patrizia, Ponzoni, Mirco, Pastorino, Ugo, Sozzi, Gabriella, Fortunato, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564655/
https://www.ncbi.nlm.nih.gov/pubmed/34107168
http://dx.doi.org/10.1002/1878-0261.13036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564655/
https://www.ncbi.nlm.nih.gov/pubmed/34107168
http://dx.doi.org/10.1002/1878-0261.13036

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