Protease‐activated receptor 1 drives and maintains ductal cell fates in the premalignant pancreas and ductal adenocarcinoma

Pancreatic acinar cells have high plasticity and can transdifferentiate into ductal‐like cells. This acinar‐to‐ductal metaplasia (ADM) contributes to tissue maintenance but may also contribute to the premalignant transformation that can eventually progress to pancreatic ductal adenocarcinoma (PDAC)....

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Detalles Bibliográficos
Autores principales: Tekin, Cansu, Scicluna, Brendon P., Lodestijn, Sophie C., Shi, Kun, Bijlsma, Maarten F., Spek, C. Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564660/
https://www.ncbi.nlm.nih.gov/pubmed/33932087
http://dx.doi.org/10.1002/1878-0261.12971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564660/
https://www.ncbi.nlm.nih.gov/pubmed/33932087
http://dx.doi.org/10.1002/1878-0261.12971

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