Non-coding RNA in cancer

Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, i...

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Detalles Bibliográficos
Autores principales: Yan, Huiwen, Bu, Pengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564738/
https://www.ncbi.nlm.nih.gov/pubmed/33860799
http://dx.doi.org/10.1042/EBC20200032
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author Yan, Huiwen
Bu, Pengcheng
author_facet Yan, Huiwen
Bu, Pengcheng
author_sort Yan, Huiwen
collection PubMed
description Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, in this review, we mainly focus on the recent studies of the function, regulatory mechanism and therapeutic potential of the ncRNAs including microRNA (miRNA), long ncRNA (lncRNA), circular RNA (circRNA) and PIWI interacting RNA (piRNA), in different type of cancers.
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spelling pubmed-85647382021-11-17 Non-coding RNA in cancer Yan, Huiwen Bu, Pengcheng Essays Biochem Cancer Majority of the human genome is transcribed to RNAs that do not encode proteins. These non-coding RNAs (ncRNAs) play crucial roles in regulating the initiation and progression of various cancers. Given the importance of the ncRNAs, the roles of ncRNAs in cancers have been reviewed elsewhere. Thus, in this review, we mainly focus on the recent studies of the function, regulatory mechanism and therapeutic potential of the ncRNAs including microRNA (miRNA), long ncRNA (lncRNA), circular RNA (circRNA) and PIWI interacting RNA (piRNA), in different type of cancers. Portland Press Ltd. 2021-10 2021-10-27 /pmc/articles/PMC8564738/ /pubmed/33860799 http://dx.doi.org/10.1042/EBC20200032 Text en © 2021 The Author(s). https://creativecommons.org/licenses/by/4.0/This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Cancer
Yan, Huiwen
Bu, Pengcheng
Non-coding RNA in cancer
title Non-coding RNA in cancer
title_full Non-coding RNA in cancer
title_fullStr Non-coding RNA in cancer
title_full_unstemmed Non-coding RNA in cancer
title_short Non-coding RNA in cancer
title_sort non-coding rna in cancer
topic Cancer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564738/
https://www.ncbi.nlm.nih.gov/pubmed/33860799
http://dx.doi.org/10.1042/EBC20200032
work_keys_str_mv AT yanhuiwen noncodingrnaincancer
AT bupengcheng noncodingrnaincancer

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