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Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience

Introduction Sclerotherapy offers an alternative to surgery to treat an aneurysmal bone cyst (ABC). The present study's main objective was to assess the radiological efficacy of sclerotherapy in the healing of the cyst cavity secondary to biopsy-proven ABC on X-rays and assess clinical efficacy...

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Autores principales: Kumar, Deepak, Kumar, Sanjeev, Kumar, Dharmendra, Patel, Brij Mohan, Kumar, Ashish, Kumar, Santosh, Waliullah, Shah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564749/
https://www.ncbi.nlm.nih.gov/pubmed/34754635
http://dx.doi.org/10.7759/cureus.18469
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author Kumar, Deepak
Kumar, Sanjeev
Kumar, Dharmendra
Patel, Brij Mohan
Kumar, Ashish
Kumar, Santosh
Waliullah, Shah
author_facet Kumar, Deepak
Kumar, Sanjeev
Kumar, Dharmendra
Patel, Brij Mohan
Kumar, Ashish
Kumar, Santosh
Waliullah, Shah
author_sort Kumar, Deepak
collection PubMed
description Introduction Sclerotherapy offers an alternative to surgery to treat an aneurysmal bone cyst (ABC). The present study's main objective was to assess the radiological efficacy of sclerotherapy in the healing of the cyst cavity secondary to biopsy-proven ABC on X-rays and assess clinical efficacy on pain, recurrence, and complications. Materials and methods Between 2016 and 2018, 26 patients (12 females, 14 males) with biopsy-proven ABC treated by sclerotherapy were included. All patients received an injection of polidocanol 3% intralesional as standard treatment under fluoroscopic guidance. Ossification was assessed on plain X-ray, and the pain was evaluated on a visual analog scale (VAS). Results Ossification was complete in 24 (92.3%) patients and partial in two (7.7%) patients. Eighteen patients (70%) were pain-free at the end of three months. There was an improvement in the VAS score, and clinically, there was a significant reduction in pain and swelling. Two patients developed recurrence within two years of follow-up, treated successfully by the re-application of intralesional polidocanol 3% injection. Discussion Sclerotherapy provides an effective, minimally invasive treatment for ABC and is particularly useful for deep lesions, challenging access for surgery and potentially damaging vital structures. The use of percutaneous polidocanol 3% under fluoroscopic control seems to improve the risk/benefit ratio. Its clinical and radiological efficacy makes sclerotherapy an alternative treatment option in ABC.  Level of evidence IV, prospective study
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spelling pubmed-85647492021-11-08 Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience Kumar, Deepak Kumar, Sanjeev Kumar, Dharmendra Patel, Brij Mohan Kumar, Ashish Kumar, Santosh Waliullah, Shah Cureus Oncology Introduction Sclerotherapy offers an alternative to surgery to treat an aneurysmal bone cyst (ABC). The present study's main objective was to assess the radiological efficacy of sclerotherapy in the healing of the cyst cavity secondary to biopsy-proven ABC on X-rays and assess clinical efficacy on pain, recurrence, and complications. Materials and methods Between 2016 and 2018, 26 patients (12 females, 14 males) with biopsy-proven ABC treated by sclerotherapy were included. All patients received an injection of polidocanol 3% intralesional as standard treatment under fluoroscopic guidance. Ossification was assessed on plain X-ray, and the pain was evaluated on a visual analog scale (VAS). Results Ossification was complete in 24 (92.3%) patients and partial in two (7.7%) patients. Eighteen patients (70%) were pain-free at the end of three months. There was an improvement in the VAS score, and clinically, there was a significant reduction in pain and swelling. Two patients developed recurrence within two years of follow-up, treated successfully by the re-application of intralesional polidocanol 3% injection. Discussion Sclerotherapy provides an effective, minimally invasive treatment for ABC and is particularly useful for deep lesions, challenging access for surgery and potentially damaging vital structures. The use of percutaneous polidocanol 3% under fluoroscopic control seems to improve the risk/benefit ratio. Its clinical and radiological efficacy makes sclerotherapy an alternative treatment option in ABC.  Level of evidence IV, prospective study Cureus 2021-10-04 /pmc/articles/PMC8564749/ /pubmed/34754635 http://dx.doi.org/10.7759/cureus.18469 Text en Copyright © 2021, Kumar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Kumar, Deepak
Kumar, Sanjeev
Kumar, Dharmendra
Patel, Brij Mohan
Kumar, Ashish
Kumar, Santosh
Waliullah, Shah
Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience
title Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience
title_full Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience
title_fullStr Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience
title_full_unstemmed Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience
title_short Sclerotherapy for Aneurysmal Bone Cyst: A Single-Center Experience
title_sort sclerotherapy for aneurysmal bone cyst: a single-center experience
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564749/
https://www.ncbi.nlm.nih.gov/pubmed/34754635
http://dx.doi.org/10.7759/cureus.18469
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