Molecular Flexibility of Antibodies Preserved Even in the Dense Phase after Macroscopic Phase Separation

[Image: see text] Antibody therapies are typically based on high-concentration formulations that need to be administered subcutaneously. These conditions induce several challenges, inter alia a viscosity suitable for injection, sufficient solution stability, and preservation of molecular function. T...

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Detalles Bibliográficos
Autores principales: Girelli, Anita, Beck, Christian, Bäuerle, Famke, Matsarskaia, Olga, Maier, Ralph, Zhang, Fajun, Wu, Baohu, Lang, Christian, Czakkel, Orsolya, Seydel, Tilo, Schreiber, Frank, Roosen-Runge, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564753/
https://www.ncbi.nlm.nih.gov/pubmed/34637319
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564753/
https://www.ncbi.nlm.nih.gov/pubmed/34637319
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00555

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