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Molecular Flexibility of Antibodies Preserved Even in the Dense Phase after Macroscopic Phase Separation

[Image: see text] Antibody therapies are typically based on high-concentration formulations that need to be administered subcutaneously. These conditions induce several challenges, inter alia a viscosity suitable for injection, sufficient solution stability, and preservation of molecular function. T...

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Detalles Bibliográficos
Autores principales:	Girelli, Anita, Beck, Christian, Bäuerle, Famke, Matsarskaia, Olga, Maier, Ralph, Zhang, Fajun, Wu, Baohu, Lang, Christian, Czakkel, Orsolya, Seydel, Tilo, Schreiber, Frank, Roosen-Runge, Felix
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564753/ https://www.ncbi.nlm.nih.gov/pubmed/34637319 http://dx.doi.org/10.1021/acs.molpharmaceut.1c00555

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