Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection

The global coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive-sense RNA virus. How the host immune system senses and responds to SARS-CoV-2 infection remain largely unresolved. Here, we report that SARS-CoV-2 infection a...

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Detalles Bibliográficos
Autores principales: Zhou, Zhuo, Zhang, Xinyi, Lei, Xiaobo, Xiao, Xia, Jiao, Tao, Ma, Ruiyi, Dong, Xiaojing, Jiang, Qi, Wang, Wenjing, Shi, Yujin, Zheng, Tian, Rao, Jian, Xiang, Zichun, Ren, Lili, Deng, Tao, Jiang, Zhengfan, Dou, Zhixun, Wei, Wensheng, Wang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564796/
https://www.ncbi.nlm.nih.gov/pubmed/34732709
http://dx.doi.org/10.1038/s41392-021-00800-3

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