Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis

Monocarboxylates, such as lactate and pyruvate, are precursors for biosynthetic pathways, including those for glucose, lipids, and amino acids via the tricarboxylic acid (TCA) cycle and adjacent metabolic networks. The transportation of monocarboxylates across the cellular membrane is performed prim...

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Detalles Bibliográficos
Autores principales: Ryuge, Akihiro, Kosugi, Tomoki, Maeda, Kayaho, Banno, Ryoichi, Gou, Yang, Zaitsu, Kei, Ito, Takanori, Sato, Yuka, Hirayama, Akiyoshi, Tsubota, Shoma, Honda, Takashi, Nakajima, Kazuki, Ozaki, Tomoya, Kondoh, Kunio, Takahashi, Kazuo, Kato, Noritoshi, Ishimoto, Takuji, Soga, Tomoyoshi, Nakagawa, Takahiko, Koike, Teruhiko, Arima, Hiroshi, Yuzawa, Yukio, Minokoshi, Yasuhiko, Maruyama, Shoichi, Kadomatsu, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564892/
https://www.ncbi.nlm.nih.gov/pubmed/34676828
http://dx.doi.org/10.1172/jci.insight.142464

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