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Super-resolution microscopy reveals photoreceptor-specific subciliary location and function of ciliopathy-associated protein CEP290

Mutations in the cilium-associated protein CEP290 cause retinal degeneration as part of multiorgan ciliopathies or as retina-specific diseases. The precise location and the functional roles of CEP290 within cilia and, specifically, the connecting cilia (CC) of photoreceptors, remain unclear. We used...

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Detalles Bibliográficos
Autores principales:	Potter, Valencia L., Moye, Abigail R., Robichaux, Michael A., Wensel, Theodore G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564900/ https://www.ncbi.nlm.nih.gov/pubmed/34520396 http://dx.doi.org/10.1172/jci.insight.145256

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