TT-10–loaded nanoparticles promote cardiomyocyte proliferation and cardiac repair in a mouse model of myocardial infarction

The meager regenerative capacity of adult mammalian hearts appears to be driven by the proliferation of endogenous cardiomyocytes; thus, strategies targeting mechanisms of cardiomyocyte cell cycle regulation, such as the Hippo/Yes-associated protein (Hippo/Yap) pathway, could lead to the development...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Wangping, Pretorius, Danielle, Zhou, Yang, Nakada, Yuji, Yang, Jinfu, Zhang, Jianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564911/
https://www.ncbi.nlm.nih.gov/pubmed/34676829
http://dx.doi.org/10.1172/jci.insight.151987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564911/
https://www.ncbi.nlm.nih.gov/pubmed/34676829
http://dx.doi.org/10.1172/jci.insight.151987

Ejemplares similares