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Fibroblast growth factor receptor fusions in cancer: opportunities and challenges

Fibroblast growth factors (FGFs) and their receptors (FGFRs) play critical roles in many biological processes and developmental functions. Chromosomal translocation of FGFRs result in the formation of chimeric FGFR fusion proteins, which often cause aberrant signaling leading to the development and...

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Detalles Bibliográficos
Autores principales:	Chen, Lingfeng, Zhang, Yanmei, Yin, Lina, Cai, Binhao, Huang, Ping, Li, Xiaokun, Liang, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564965/ https://www.ncbi.nlm.nih.gov/pubmed/34732230 http://dx.doi.org/10.1186/s13046-021-02156-6

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