Involvement of classic and alternative non-homologous end joining pathways in hematologic malignancies: targeting strategies for treatment

Chromosomal translocations are the main etiological factor of hematologic malignancies. These translocations are generally the consequence of aberrant DNA double-strand break (DSB) repair. DSBs arise either exogenously or endogenously in cells and are repaired by major pathways, including non-homolo...

Descripción completa

Detalles Bibliográficos
Autores principales: Valikhani, Mohsen, Rahimian, Elahe, Ahmadi, Seyed Esmaeil, Chegeni, Rouzbeh, Safa, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564991/
https://www.ncbi.nlm.nih.gov/pubmed/34732266
http://dx.doi.org/10.1186/s40164-021-00242-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564991/
https://www.ncbi.nlm.nih.gov/pubmed/34732266
http://dx.doi.org/10.1186/s40164-021-00242-1

Ejemplares similares