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Involvement of classic and alternative non-homologous end joining pathways in hematologic malignancies: targeting strategies for treatment

Chromosomal translocations are the main etiological factor of hematologic malignancies. These translocations are generally the consequence of aberrant DNA double-strand break (DSB) repair. DSBs arise either exogenously or endogenously in cells and are repaired by major pathways, including non-homolo...

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Detalles Bibliográficos
Autores principales:	Valikhani, Mohsen, Rahimian, Elahe, Ahmadi, Seyed Esmaeil, Chegeni, Rouzbeh, Safa, Majid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8564991/ https://www.ncbi.nlm.nih.gov/pubmed/34732266 http://dx.doi.org/10.1186/s40164-021-00242-1

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