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Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study
BACKGROUND: Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this study was to assess these factors as potential barriers to adherence among patie...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565028/ https://www.ncbi.nlm.nih.gov/pubmed/34727943 http://dx.doi.org/10.1186/s12981-021-00405-4 |
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author | Dorcélus, Ludentz Bernard, Joseph Georgery, Constant Vanessa, Clerveau |
author_facet | Dorcélus, Ludentz Bernard, Joseph Georgery, Constant Vanessa, Clerveau |
author_sort | Dorcélus, Ludentz |
collection | PubMed |
description | BACKGROUND: Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this study was to assess these factors as potential barriers to adherence among patients receiving care in central Haiti. METHODS: A cross-sectional study was conducted among PLH receiving antiretroviral therapy (ART) at the TB/HIV clinic at St. Therese Hospital in Hinche, Haiti. A total of 426 potential participants were approached during their follow-up visits from June to August 2019, of whom 411 participated in the study. After giving informed consent, study participants completed a structured interview that included the Self-Report Item Scale (SRIS), a standard measure, to assess adherence. Socio-demographic, economic and clinical factors were assessed for their association with adherence. RESULTS: The 411 participating patients represented 39% of the patient population at the TB/HIV clinic during the timeframe of the study. The mean age was 43.7 years (range: 19–80), 65.5% were female and 78.1% had only achieved a primary level of schooling. Nearly 78% had received ART for less than 10 years, 3.41% reported having poor adherence and 28% less than excellent adherence. Factors related to poor adherence in bivariate analysis were age less than 40 years (OR: 6.32, 95% CI 2.04–10.58, p < 0.01) and inability to meet basic needs (OR: 2.70, 95% CI 1.04–7.0, p = 0.03). CONCLUSIONS: To improve medication adherence, the hospital should strengthen patient counselling of younger recipients of ART and provide financial assistance and other social service interventions. Studies should be implemented in other HIV management centers in Haiti and similar contexts to examine barriers to ART adherence with the goal of improving prognosis and survival in the long-term among PLH in resource-limited setting. |
format | Online Article Text |
id | pubmed-8565028 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-85650282021-11-04 Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study Dorcélus, Ludentz Bernard, Joseph Georgery, Constant Vanessa, Clerveau AIDS Res Ther Research BACKGROUND: Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this study was to assess these factors as potential barriers to adherence among patients receiving care in central Haiti. METHODS: A cross-sectional study was conducted among PLH receiving antiretroviral therapy (ART) at the TB/HIV clinic at St. Therese Hospital in Hinche, Haiti. A total of 426 potential participants were approached during their follow-up visits from June to August 2019, of whom 411 participated in the study. After giving informed consent, study participants completed a structured interview that included the Self-Report Item Scale (SRIS), a standard measure, to assess adherence. Socio-demographic, economic and clinical factors were assessed for their association with adherence. RESULTS: The 411 participating patients represented 39% of the patient population at the TB/HIV clinic during the timeframe of the study. The mean age was 43.7 years (range: 19–80), 65.5% were female and 78.1% had only achieved a primary level of schooling. Nearly 78% had received ART for less than 10 years, 3.41% reported having poor adherence and 28% less than excellent adherence. Factors related to poor adherence in bivariate analysis were age less than 40 years (OR: 6.32, 95% CI 2.04–10.58, p < 0.01) and inability to meet basic needs (OR: 2.70, 95% CI 1.04–7.0, p = 0.03). CONCLUSIONS: To improve medication adherence, the hospital should strengthen patient counselling of younger recipients of ART and provide financial assistance and other social service interventions. Studies should be implemented in other HIV management centers in Haiti and similar contexts to examine barriers to ART adherence with the goal of improving prognosis and survival in the long-term among PLH in resource-limited setting. BioMed Central 2021-11-02 /pmc/articles/PMC8565028/ /pubmed/34727943 http://dx.doi.org/10.1186/s12981-021-00405-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Dorcélus, Ludentz Bernard, Joseph Georgery, Constant Vanessa, Clerveau Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study |
title | Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study |
title_full | Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study |
title_fullStr | Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study |
title_full_unstemmed | Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study |
title_short | Factors associated with antiretroviral therapy adherence among people living with HIV in Haiti: a cross-sectional study |
title_sort | factors associated with antiretroviral therapy adherence among people living with hiv in haiti: a cross-sectional study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565028/ https://www.ncbi.nlm.nih.gov/pubmed/34727943 http://dx.doi.org/10.1186/s12981-021-00405-4 |
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