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Inhibition of protein tyrosine phosphatase improves mitochondrial bioenergetics and dynamics, reduces oxidative stress, and enhances adipogenic differentiation potential in metabolically impaired progenitor stem cells

BACKGROUND: Protein tyrosine phosphatase 1B (PTP1B) and low molecular weight protein tyrosine phosphatase (LMPTP) are implicated in the development of metabolic disorders. Yet, their role in progenitor stem cell adipogenic differentiation and modulation of mitochondrial dynamics remains elusive. MET...

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Detalles Bibliográficos
Autores principales:	Kornicka-Garbowska, Katarzyna, Bourebaba, Lynda, Röcken, Michael, Marycz, Krzysztof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565043/ https://www.ncbi.nlm.nih.gov/pubmed/34732209 http://dx.doi.org/10.1186/s12964-021-00772-5

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