Beclin1 controls caspase-4 inflammsome activation and pyroptosis in mouse myocardial reperfusion-induced microvascular injury

BACKGROUND: Myocardial reperfusion injury is often accompanied by cell death and inflammatory reactions. Recently, pyroptosis is gradually recognized as pivotal role in cardiovascular disease. However, little is known about the regulatory role of beclin1 in the control of caspase-4 activation and py...

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Detalles Bibliográficos
Autores principales: Sun, Wenjing, Lu, Hongquan, Dong, Shujuan, Li, Rui, Chu, Yingjie, Wang, Nan, Zhao, Yu, Zhang, Yabin, Wang, Limeiting, Sun, Lin, Lu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565084/
https://www.ncbi.nlm.nih.gov/pubmed/34732218
http://dx.doi.org/10.1186/s12964-021-00786-z

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