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Sociodemographic and clinical characteristics associated with COVID mortality among hospitalized patients in Rajasthan: A retrospective observational study

BACKGROUND: It has been over a year since the declaration of novel coronavirus disease (COVID-19) as pandemic by World Health Organization on March 11, 2020. Although mortality in India is low, as compared to western countries, the steady increase in the number of cases is still a worrying sign. The...

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Autores principales: Verma, Anjana, Patyal, Ashish, Mathur, Medha, Choudhary, Suresh, Mathur, Navgeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565107/
https://www.ncbi.nlm.nih.gov/pubmed/34760751
http://dx.doi.org/10.4103/jfmpc.jfmpc_445_21
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author Verma, Anjana
Patyal, Ashish
Mathur, Medha
Choudhary, Suresh
Mathur, Navgeet
author_facet Verma, Anjana
Patyal, Ashish
Mathur, Medha
Choudhary, Suresh
Mathur, Navgeet
author_sort Verma, Anjana
collection PubMed
description BACKGROUND: It has been over a year since the declaration of novel coronavirus disease (COVID-19) as pandemic by World Health Organization on March 11, 2020. Although mortality in India is low, as compared to western countries, the steady increase in the number of cases is still a worrying sign. The objectives of this study were to identify and quantify the association between sociodemographic and clinical characteristics with mortality among patients, suffering from COVID-19 at a tertiary care hospital in Udaipur, Rajasthan. MATERIAL AND METHODS: This retrospective observational study involved 824 patients hospitalized for COVID 19 at a tertiary hospital in Udaipur, who were discharged or had died. Electronic health records of the patients were accessed to retrieve the sociodemographic information (age, gender, residence, religion, socioeconomic status), history of exposure, clinical characteristics on admission, comorbidities, and outcomes (recovery or death). The Cox regression model was used to calculate associations between mortality and baseline characteristics in the form of hazard ratios (HRs). RESULTS: Mortality in this study was found to be 5.82%. The mean age of the patients was 48.14 ± 16.2 years. The median time from time of admission to discharge was 8 days (interquartile range (IQR) 5–11), whereas the median time to death was 5 days (IQR 4–10). The variables found to be associated with higher mortality were age (HR 1.17; 95% confidence interval (CI) 1.15–1.24), residing in urban area (HR 1.29; 95% CI 1.17–2.15), diabetes mellitus (HR 1.3; CI 1.02–5.57), and patients having both diabetes and hypertension (HR 2.4; CI 1.69–3.14). CONCLUSION: Sociodemographic variables and comorbidities impact the mortality among COVID 19 patients. The variables most clearly associated with a greater hazard of death were older age, urban area, diabetes, and having both diabetes and hypertension.
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spelling pubmed-85651072021-11-09 Sociodemographic and clinical characteristics associated with COVID mortality among hospitalized patients in Rajasthan: A retrospective observational study Verma, Anjana Patyal, Ashish Mathur, Medha Choudhary, Suresh Mathur, Navgeet J Family Med Prim Care Original Article BACKGROUND: It has been over a year since the declaration of novel coronavirus disease (COVID-19) as pandemic by World Health Organization on March 11, 2020. Although mortality in India is low, as compared to western countries, the steady increase in the number of cases is still a worrying sign. The objectives of this study were to identify and quantify the association between sociodemographic and clinical characteristics with mortality among patients, suffering from COVID-19 at a tertiary care hospital in Udaipur, Rajasthan. MATERIAL AND METHODS: This retrospective observational study involved 824 patients hospitalized for COVID 19 at a tertiary hospital in Udaipur, who were discharged or had died. Electronic health records of the patients were accessed to retrieve the sociodemographic information (age, gender, residence, religion, socioeconomic status), history of exposure, clinical characteristics on admission, comorbidities, and outcomes (recovery or death). The Cox regression model was used to calculate associations between mortality and baseline characteristics in the form of hazard ratios (HRs). RESULTS: Mortality in this study was found to be 5.82%. The mean age of the patients was 48.14 ± 16.2 years. The median time from time of admission to discharge was 8 days (interquartile range (IQR) 5–11), whereas the median time to death was 5 days (IQR 4–10). The variables found to be associated with higher mortality were age (HR 1.17; 95% confidence interval (CI) 1.15–1.24), residing in urban area (HR 1.29; 95% CI 1.17–2.15), diabetes mellitus (HR 1.3; CI 1.02–5.57), and patients having both diabetes and hypertension (HR 2.4; CI 1.69–3.14). CONCLUSION: Sociodemographic variables and comorbidities impact the mortality among COVID 19 patients. The variables most clearly associated with a greater hazard of death were older age, urban area, diabetes, and having both diabetes and hypertension. Wolters Kluwer - Medknow 2021-09 2021-09-30 /pmc/articles/PMC8565107/ /pubmed/34760751 http://dx.doi.org/10.4103/jfmpc.jfmpc_445_21 Text en Copyright: © 2021 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Verma, Anjana
Patyal, Ashish
Mathur, Medha
Choudhary, Suresh
Mathur, Navgeet
Sociodemographic and clinical characteristics associated with COVID mortality among hospitalized patients in Rajasthan: A retrospective observational study
title Sociodemographic and clinical characteristics associated with COVID mortality among hospitalized patients in Rajasthan: A retrospective observational study
title_full Sociodemographic and clinical characteristics associated with COVID mortality among hospitalized patients in Rajasthan: A retrospective observational study
title_fullStr Sociodemographic and clinical characteristics associated with COVID mortality among hospitalized patients in Rajasthan: A retrospective observational study
title_full_unstemmed Sociodemographic and clinical characteristics associated with COVID mortality among hospitalized patients in Rajasthan: A retrospective observational study
title_short Sociodemographic and clinical characteristics associated with COVID mortality among hospitalized patients in Rajasthan: A retrospective observational study
title_sort sociodemographic and clinical characteristics associated with covid mortality among hospitalized patients in rajasthan: a retrospective observational study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565107/
https://www.ncbi.nlm.nih.gov/pubmed/34760751
http://dx.doi.org/10.4103/jfmpc.jfmpc_445_21
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