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Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate

Whole genome bisulphite sequencing (WGBS) permits the genome-wide study of single molecule methylation patterns. One of the key goals of mammalian cell-type identity studies, in both normal differentiation and disease, is to locate differential methylation patterns across the genome. We discuss the...

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Detalles Bibliográficos
Autores principales: Peters, Timothy J, Buckley, Michael J, Chen, Yunshun, Smyth, Gordon K, Goodnow, Christopher C, Clark, Susan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565305/
https://www.ncbi.nlm.nih.gov/pubmed/34320181
http://dx.doi.org/10.1093/nar/gkab637