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USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing

Mutual crosstalk among poly(ADP-ribose) (PAR), activated PAR polymerase 1 (PARP1) metabolites, and DNA repair machinery has emerged as a key regulatory mechanism of the DNA damage response (DDR). However, there is no conclusive evidence of how PAR precisely controls DDR. Herein, six deubiquitinating...

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Detalles Bibliográficos
Autores principales:	Kim, Jae Jin, Lee, Seo Yun, Hwang, Yiseul, Kim, Soyeon, Chung, Jee Min, Park, Sangwook, Yoon, Junghyun, Yun, Hansol, Ji, Jae-Hoon, Chae, Sunyoung, Cho, Hyeseong, Kim, Chan Gil, Dawson, Ted M, Kim, Hongtae, Dawson, Valina L, Kang, Ho Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565343/ https://www.ncbi.nlm.nih.gov/pubmed/34614178 http://dx.doi.org/10.1093/nar/gkab892

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