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Bacteriophage Twort protein Gp168 is a β-clamp inhibitor by occupying the DNA sliding channel
Bacterial chromosome replication is mainly catalyzed by DNA polymerase III, whose beta subunits enable rapid processive DNA replication. Enabled by the clamp-loading complex, the two beta subunits form a ring-like clamp around DNA and keep the polymerase sliding along. Given the essential role of β-...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565349/ https://www.ncbi.nlm.nih.gov/pubmed/34614154 http://dx.doi.org/10.1093/nar/gkab875 |