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Inhibition of (dppf)nickel-catalysed Suzuki–Miyaura cross-coupling reactions by α-halo-N-heterocycles

A nickel/dppf catalyst system was found to successfully achieve the Suzuki–Miyaura cross-coupling reactions of 3- and 4-chloropyridine and of 6-chloroquinoline but not of 2-chloropyridine or of other α-halo-N-heterocycles. Further investigations revealed that chloropyridines undergo rapid oxidative...

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Detalles Bibliográficos
Autores principales: Cooper, Alasdair K., Greaves, Megan E., Donohoe, William, Burton, Paul M., Ronson, Thomas O., Kennedy, Alan R., Nelson, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565371/
https://www.ncbi.nlm.nih.gov/pubmed/34760191
http://dx.doi.org/10.1039/d1sc04582b

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