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Diabetes coexistent with Charcot–Marie–Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: A case report

Both diabetes mellitus and Charcot–Marie–Tooth disease (CMT) can lead to severe peripheral neuropathy. The differential diagnosis of peripheral neuropathy is difficult due to the similar clinical features. There are still some clues, such as unusual muscle atrophy, unmatched severity of peripheral n...

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Autores principales: Yan, Zhe, Chen, Dawei, Yao, Li, Wang, Chun, Ran, Xing‐Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565404/
https://www.ncbi.nlm.nih.gov/pubmed/33991180
http://dx.doi.org/10.1111/jdi.13574
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author Yan, Zhe
Chen, Dawei
Yao, Li
Wang, Chun
Ran, Xing‐Wu
author_facet Yan, Zhe
Chen, Dawei
Yao, Li
Wang, Chun
Ran, Xing‐Wu
author_sort Yan, Zhe
collection PubMed
description Both diabetes mellitus and Charcot–Marie–Tooth disease (CMT) can lead to severe peripheral neuropathy. The differential diagnosis of peripheral neuropathy is difficult due to the similar clinical features. There are still some clues, such as unusual muscle atrophy, unmatched severity of peripheral neurogenic damage with nephropathy or retinopathy, which could alert clinicians to make differential diagnosis. Although diabetes mellitus is rarely concurrent with CMT, it will exacerbate clinical disorders in patients with CMT. To date, there is no specific medicine for CMT treatment. Offloading devices and desirable comprehensive management of diabetes mellitus might be beneficial to avoid plantar ulcer recurrence and anti‐progression of CMT.
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spelling pubmed-85654042021-11-09 Diabetes coexistent with Charcot–Marie–Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: A case report Yan, Zhe Chen, Dawei Yao, Li Wang, Chun Ran, Xing‐Wu J Diabetes Investig Articles Both diabetes mellitus and Charcot–Marie–Tooth disease (CMT) can lead to severe peripheral neuropathy. The differential diagnosis of peripheral neuropathy is difficult due to the similar clinical features. There are still some clues, such as unusual muscle atrophy, unmatched severity of peripheral neurogenic damage with nephropathy or retinopathy, which could alert clinicians to make differential diagnosis. Although diabetes mellitus is rarely concurrent with CMT, it will exacerbate clinical disorders in patients with CMT. To date, there is no specific medicine for CMT treatment. Offloading devices and desirable comprehensive management of diabetes mellitus might be beneficial to avoid plantar ulcer recurrence and anti‐progression of CMT. John Wiley and Sons Inc. 2021-06-06 2021-11 /pmc/articles/PMC8565404/ /pubmed/33991180 http://dx.doi.org/10.1111/jdi.13574 Text en © 2021 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Articles
Yan, Zhe
Chen, Dawei
Yao, Li
Wang, Chun
Ran, Xing‐Wu
Diabetes coexistent with Charcot–Marie–Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: A case report
title Diabetes coexistent with Charcot–Marie–Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: A case report
title_full Diabetes coexistent with Charcot–Marie–Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: A case report
title_fullStr Diabetes coexistent with Charcot–Marie–Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: A case report
title_full_unstemmed Diabetes coexistent with Charcot–Marie–Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: A case report
title_short Diabetes coexistent with Charcot–Marie–Tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: A case report
title_sort diabetes coexistent with charcot–marie–tooth disease presenting as a recurrent foot ulcer misdiagnosed as diabetic foot: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565404/
https://www.ncbi.nlm.nih.gov/pubmed/33991180
http://dx.doi.org/10.1111/jdi.13574
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