The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly

Ciliary motility is powered by a suite of highly conserved axoneme-specific dynein motor complexes. In humans, the impairment of these motors through mutation results in the disease primary ciliary dyskinesia (PCD). Studies in Drosophila have helped to validate several PCD genes whose products are r...

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Detalles Bibliográficos
Autores principales: zur Lage, Petra, Xi, Zhiyan, Lennon, Jennifer, Hunter, Iain, Chan, Wai Kit, Bolado Carrancio, Alfonso, von Kriegsheim, Alex, Jarman, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565470/
https://www.ncbi.nlm.nih.gov/pubmed/34553759
http://dx.doi.org/10.1242/bio.058812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565470/
https://www.ncbi.nlm.nih.gov/pubmed/34553759
http://dx.doi.org/10.1242/bio.058812

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