Cargando…

Bloom Helicase Along with Recombinase Rad51 Repairs the Mitochondrial Genome of the Malaria Parasite

The homologous recombination (HR) pathway has been implicated as the predominant mechanism for the repair of chromosomal DNA double-strand breaks (DSBs) of the malarial parasite. Although the extrachromosomal mitochondrial genome of this parasite experiences a greater number of DSBs due to its close...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jha, Payal, Gahlawat, Abhilasha, Bhattacharyya, Sunanda, Dey, Sandeep, Kumar, Kota Arun, Bhattacharyya, Mrinal Kanti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565512/ https://www.ncbi.nlm.nih.gov/pubmed/34730376 http://dx.doi.org/10.1128/mSphere.00718-21

Ejemplares similares

Characterization of Rad51 from Apicomplexan Parasite Toxoplasma gondii: An Implication for Inefficient Gene Targeting
por: Achanta, Sita Swati, et al.
Publicado: (2012)

Uncovering the role of Rad51 in homologous recombination-mediated antigenic diversification in the human malaria parasite Plasmodium falciparum
por: Vydyam, Pratap, et al.
Publicado: (2023)

Elucidation of DNA Repair Function of PfBlm and Potentiation of Artemisinin Action by a Small-Molecule Inhibitor of RecQ Helicase
por: Suthram, Niranjan, et al.
Publicado: (2020)

Physical Interaction of RECQ5 Helicase with RAD51 Facilitates Its Anti-recombinase Activity
por: Schwendener, Sybille, et al.
Publicado: (2010)

Glu-108 in Saccharomyces cerevisiae Rad51 Is Critical for DNA Damage-Induced Nuclear Function
por: Suhane, Tanvi, et al.
Publicado: (2019)

Rad51 paralogs Rad55-Rad57 balance the anti-recombinase Srs2 in Rad51 filament formation
por: Liu, Jie, et al.
Publicado: (2011)

ATP half‐sites in RadA and RAD51 recombinases bind nucleotides
por: Marsh, May E., et al.
Publicado: (2016)

Plasmodium Topoisomerase VIB and Spo11 Constitute Functional Type IIB Topoisomerase in Malaria Parasite: Its Possible Role in Mitochondrial DNA Segregation
por: Singh, Priyanka, et al.
Publicado: (2023)

The RAD51 recombinase protects mitotic chromatin in human cells
por: Wassing, Isabel E., et al.
Publicado: (2021)

Radicicol-Mediated Inhibition of Topoisomerase VIB-VIA Activity of the Human Malaria Parasite Plasmodium falciparum
por: Chalapareddy, Sureshkumar, et al.
Publicado: (2016)

Enhancement of the RAD51 Recombinase Activity by the Tumor Suppressor PALB2
por: Dray, Eloïse, et al.
Publicado: (2010)

Hsp90 induces increased genomic instability toward DNA-damaging agents by tuning down RAD53 transcription
por: Khurana, Nidhi, et al.
Publicado: (2016)

Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase
por: Matsuzaki, Kenichiro, et al.
Publicado: (2019)

Rad52 Sumoylation Prevents the Toxicity of Unproductive Rad51 Filaments Independently of the Anti-Recombinase Srs2
por: Esta, Aline, et al.
Publicado: (2013)

Small-Molecule Inhibitors That Target Protein–Protein Interactions in the RAD51 Family of Recombinases
por: Scott, Duncan E, et al.
Publicado: (2015)

Detection of novel recombinases in bacteriophage genomes unveils Rad52, Rad51 and Gp2.5 remote homologs
por: Lopes, Anne, et al.
Publicado: (2010)

Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant
por: Chen, Jianhong, et al.
Publicado: (2010)

The recombinase Rad51 plays a key role in events of genetic exchange in Trypanosoma cruzi
por: Alves, Ceres Luciana, et al.
Publicado: (2018)

Ataxia-televangelist mutated (ATM)/ ATR serine/threonine kinase (ATR)-mediated RAD51 recombinase (RAD51) promotes osteogenic differentiation and inhibits osteoclastogenesis in osteoporosis
por: Qiu, Minli, et al.
Publicado: (2022)

Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA
por: Gyimesi, Máté, et al.
Publicado: (2010)

Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases
por: Ploquin, Mickaël, et al.
Publicado: (2007)

Subunit Interface Residues F129 and H294 of Human RAD51 Are Essential for Recombinase Function
por: Amunugama, Ravindra, et al.
Publicado: (2011)

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase
por: Rajendra, Eeson, et al.
Publicado: (2010)

DNA damage-induced nuclear import of HSP90α is promoted by Aha1
por: Fangaria, Nupur, et al.
Publicado: (2022)

The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments
por: Crickard, J Brooks, et al.
Publicado: (2019)

Roles of XRCC2, RAD51B and RAD51D in RAD51-Independent SSA Recombination
por: Serra, Heïdi, et al.
Publicado: (2013)

Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures
por: Luo, Shih-Chi, et al.
Publicado: (2021)

Human RAD51 paralogue RAD51C fosters repair of alkylated DNA by interacting with the ALKBH3 demethylase
por: Mohan, Monisha, et al.
Publicado: (2019)

Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor
por: Greenhough, Luke A., et al.
Publicado: (2023)

Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease Function
por: Badugu, Sugith Babu, et al.
Publicado: (2015)

Correction: Identification of Plasmodium falciparum DNA Repair Protein Mre11 with an Evolutionarily Conserved Nuclease Function
por: Badugu, Sugith Babu, et al.
Publicado: (2023)

Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs
por: Takata, Kei-ichi, et al.
Publicado: (2013)

RAD51 and MRE11 dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks
por: Hashimoto, Yoshitami, et al.
Publicado: (2011)

RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
por: Randolph, Matthew E., et al.
Publicado: (2023)

Transcriptional profile of the homologous recombination machinery and characterization of the EhRAD51 recombinase in response to DNA damage in Entamoeba histolytica
por: López-Casamichana, Mavil, et al.
Publicado: (2008)

Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase
por: Chen, Jianhong, et al.
Publicado: (2015)

Homologous Pairing Activities of Two Rice RAD51 Proteins, RAD51A1 and RAD51A2
por: Morozumi, Yuichi, et al.
Publicado: (2013)

FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability
por: Liu, Wenpeng, et al.
Publicado: (2023)

The Recombinases Rad51 and Dmc1 Play Distinct Roles in DNA Break Repair and Recombination Partner Choice in the Meiosis of Tetrahymena
por: Howard-Till, Rachel A., et al.
Publicado: (2011)

The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase
por: Bernstein, Kara A., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ae2ersqansink6jsijretamc5v