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A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role

PURPOSE: Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete...

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Autores principales: Piórek, Aleksandra, Tabor, Sylwia, Jaśkiewicz, Piotr, Kasprowicz, Anetta, Zaborowska-Szmit, Magdalena, Winiarczyk, Kinga, Płużański, Adam, Kowalski, Dariusz, Krzakowski, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565636/
https://www.ncbi.nlm.nih.gov/pubmed/34759984
http://dx.doi.org/10.5114/jcb.2021.109853
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author Piórek, Aleksandra
Tabor, Sylwia
Jaśkiewicz, Piotr
Kasprowicz, Anetta
Zaborowska-Szmit, Magdalena
Winiarczyk, Kinga
Płużański, Adam
Kowalski, Dariusz
Krzakowski, Maciej
author_facet Piórek, Aleksandra
Tabor, Sylwia
Jaśkiewicz, Piotr
Kasprowicz, Anetta
Zaborowska-Szmit, Magdalena
Winiarczyk, Kinga
Płużański, Adam
Kowalski, Dariusz
Krzakowski, Maciej
author_sort Piórek, Aleksandra
collection PubMed
description PURPOSE: Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete excision. There are no available prospective data on post-relapse treatment. CASE PRESENTATION: The current paper presents a case of tracheal ACC in a young woman, treated solely with surgical resection without radiotherapy due to postoperative neurological complications requiring additional diagnostics, management, and treatment. As a complication itself, spinal cord dysfunction after tracheal surgery is extremely rare, in which radical radiotherapy and brachytherapy were successfully administered after disease recurrence. CONCLUSIONS: Lack of post-operative radiotherapy resulting from neurological complications could be a reason for ACC recurrence in our patient. Administration of radiotherapy after incomplete resection of recurrent disease may lead to long-term locoregional control.
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spelling pubmed-85656362021-11-09 A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role Piórek, Aleksandra Tabor, Sylwia Jaśkiewicz, Piotr Kasprowicz, Anetta Zaborowska-Szmit, Magdalena Winiarczyk, Kinga Płużański, Adam Kowalski, Dariusz Krzakowski, Maciej J Contemp Brachytherapy Case Report PURPOSE: Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete excision. There are no available prospective data on post-relapse treatment. CASE PRESENTATION: The current paper presents a case of tracheal ACC in a young woman, treated solely with surgical resection without radiotherapy due to postoperative neurological complications requiring additional diagnostics, management, and treatment. As a complication itself, spinal cord dysfunction after tracheal surgery is extremely rare, in which radical radiotherapy and brachytherapy were successfully administered after disease recurrence. CONCLUSIONS: Lack of post-operative radiotherapy resulting from neurological complications could be a reason for ACC recurrence in our patient. Administration of radiotherapy after incomplete resection of recurrent disease may lead to long-term locoregional control. Termedia Publishing House 2021-10-08 2021-10 /pmc/articles/PMC8565636/ /pubmed/34759984 http://dx.doi.org/10.5114/jcb.2021.109853 Text en Copyright © 2021 Termedia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) )
spellingShingle Case Report
Piórek, Aleksandra
Tabor, Sylwia
Jaśkiewicz, Piotr
Kasprowicz, Anetta
Zaborowska-Szmit, Magdalena
Winiarczyk, Kinga
Płużański, Adam
Kowalski, Dariusz
Krzakowski, Maciej
A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role
title A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role
title_full A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role
title_fullStr A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role
title_full_unstemmed A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role
title_short A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role
title_sort case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565636/
https://www.ncbi.nlm.nih.gov/pubmed/34759984
http://dx.doi.org/10.5114/jcb.2021.109853
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