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A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role
PURPOSE: Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565636/ https://www.ncbi.nlm.nih.gov/pubmed/34759984 http://dx.doi.org/10.5114/jcb.2021.109853 |
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author | Piórek, Aleksandra Tabor, Sylwia Jaśkiewicz, Piotr Kasprowicz, Anetta Zaborowska-Szmit, Magdalena Winiarczyk, Kinga Płużański, Adam Kowalski, Dariusz Krzakowski, Maciej |
author_facet | Piórek, Aleksandra Tabor, Sylwia Jaśkiewicz, Piotr Kasprowicz, Anetta Zaborowska-Szmit, Magdalena Winiarczyk, Kinga Płużański, Adam Kowalski, Dariusz Krzakowski, Maciej |
author_sort | Piórek, Aleksandra |
collection | PubMed |
description | PURPOSE: Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete excision. There are no available prospective data on post-relapse treatment. CASE PRESENTATION: The current paper presents a case of tracheal ACC in a young woman, treated solely with surgical resection without radiotherapy due to postoperative neurological complications requiring additional diagnostics, management, and treatment. As a complication itself, spinal cord dysfunction after tracheal surgery is extremely rare, in which radical radiotherapy and brachytherapy were successfully administered after disease recurrence. CONCLUSIONS: Lack of post-operative radiotherapy resulting from neurological complications could be a reason for ACC recurrence in our patient. Administration of radiotherapy after incomplete resection of recurrent disease may lead to long-term locoregional control. |
format | Online Article Text |
id | pubmed-8565636 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-85656362021-11-09 A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role Piórek, Aleksandra Tabor, Sylwia Jaśkiewicz, Piotr Kasprowicz, Anetta Zaborowska-Szmit, Magdalena Winiarczyk, Kinga Płużański, Adam Kowalski, Dariusz Krzakowski, Maciej J Contemp Brachytherapy Case Report PURPOSE: Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete excision. There are no available prospective data on post-relapse treatment. CASE PRESENTATION: The current paper presents a case of tracheal ACC in a young woman, treated solely with surgical resection without radiotherapy due to postoperative neurological complications requiring additional diagnostics, management, and treatment. As a complication itself, spinal cord dysfunction after tracheal surgery is extremely rare, in which radical radiotherapy and brachytherapy were successfully administered after disease recurrence. CONCLUSIONS: Lack of post-operative radiotherapy resulting from neurological complications could be a reason for ACC recurrence in our patient. Administration of radiotherapy after incomplete resection of recurrent disease may lead to long-term locoregional control. Termedia Publishing House 2021-10-08 2021-10 /pmc/articles/PMC8565636/ /pubmed/34759984 http://dx.doi.org/10.5114/jcb.2021.109853 Text en Copyright © 2021 Termedia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) ) |
spellingShingle | Case Report Piórek, Aleksandra Tabor, Sylwia Jaśkiewicz, Piotr Kasprowicz, Anetta Zaborowska-Szmit, Magdalena Winiarczyk, Kinga Płużański, Adam Kowalski, Dariusz Krzakowski, Maciej A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role |
title | A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role |
title_full | A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role |
title_fullStr | A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role |
title_full_unstemmed | A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role |
title_short | A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role |
title_sort | case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565636/ https://www.ncbi.nlm.nih.gov/pubmed/34759984 http://dx.doi.org/10.5114/jcb.2021.109853 |
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