A rare case of NXP-2 positive dermatomyositis

Dermatomyositis is an idiopathic inflammatory myopathy with variable cutaneous manifestations. Several autoantibodies each with distinct clinical phenotypes are associated with the disease. Here we present the case of a 36-year-old Laotian woman with hypothyroidism who presented with severe proximal...

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Detalles Bibliográficos
Autores principales: Khan, Nariman, Kazmi, Zehra Hasan, Alkhateb, Rahaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: UMF “Gr. T. Popa” Iasi Publishing House 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565706/
https://www.ncbi.nlm.nih.gov/pubmed/34754931
http://dx.doi.org/10.22551/2020.29.0704.10176
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author Khan, Nariman
Kazmi, Zehra Hasan
Alkhateb, Rahaf
author_facet Khan, Nariman
Kazmi, Zehra Hasan
Alkhateb, Rahaf
author_sort Khan, Nariman
collection PubMed
description Dermatomyositis is an idiopathic inflammatory myopathy with variable cutaneous manifestations. Several autoantibodies each with distinct clinical phenotypes are associated with the disease. Here we present the case of a 36-year-old Laotian woman with hypothyroidism who presented with severe proximal and distal muscle weakness, dysphagia, diffuse rash, and anasarca that was diagnosed with NXP-2 (nuclear matrix protein 2) antibody positive dermatomyositis. The patient's hospitalization was complicated by disease resistant to conventional therapy.
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spelling pubmed-85657062021-11-08 A rare case of NXP-2 positive dermatomyositis Khan, Nariman Kazmi, Zehra Hasan Alkhateb, Rahaf Arch Clin Cases Case Report Dermatomyositis is an idiopathic inflammatory myopathy with variable cutaneous manifestations. Several autoantibodies each with distinct clinical phenotypes are associated with the disease. Here we present the case of a 36-year-old Laotian woman with hypothyroidism who presented with severe proximal and distal muscle weakness, dysphagia, diffuse rash, and anasarca that was diagnosed with NXP-2 (nuclear matrix protein 2) antibody positive dermatomyositis. The patient's hospitalization was complicated by disease resistant to conventional therapy. UMF “Gr. T. Popa” Iasi Publishing House 2021-10-27 /pmc/articles/PMC8565706/ /pubmed/34754931 http://dx.doi.org/10.22551/2020.29.0704.10176 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Khan, Nariman
Kazmi, Zehra Hasan
Alkhateb, Rahaf
A rare case of NXP-2 positive dermatomyositis
title A rare case of NXP-2 positive dermatomyositis
title_full A rare case of NXP-2 positive dermatomyositis
title_fullStr A rare case of NXP-2 positive dermatomyositis
title_full_unstemmed A rare case of NXP-2 positive dermatomyositis
title_short A rare case of NXP-2 positive dermatomyositis
title_sort rare case of nxp-2 positive dermatomyositis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565706/
https://www.ncbi.nlm.nih.gov/pubmed/34754931
http://dx.doi.org/10.22551/2020.29.0704.10176
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