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Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice

BACKGROUND: Pemphigus vulgaris (PV) is a rare autoimmune blistering disease characterized by the development of autoantibodies targeting desmoglein (Dsg) 3, but also against Dsg1 in mucocutaneous disease. Given that existing PV animal models only recapitulate aspects of the disease, we aimed to esta...

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Detalles Bibliográficos
Autores principales:	Boch, Katharina, Dräger, Sören, Zillikens, Detlef, Hudemann, Christoph, Hammers, Christoph M., Patzelt, Sabrina, Schmidt, Enno, Langan, Ewan A., Eming, Rüdiger, Ludwig, Ralf J., Bieber, Katja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565724/ https://www.ncbi.nlm.nih.gov/pubmed/34731225 http://dx.doi.org/10.1371/journal.pone.0259586

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