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Sprouty1 regulates gonadal white adipose tissue growth through a PDGFRα/β-Akt pathway
Expansion of visceral white adipose tissue (vWAT) occurs in response to nutrient excess, and is a risk factor for metabolic disease. SPRY1, a feedback inhibitor of receptor tyrosine kinase (RTK) signaling, is expressed in PDGFRa+ adipocyte progenitor cells (APC) in vivo. Global deficiency of Spry1 i...
Autores principales: | Yang, Xuehui, Pande, Shivangi, Koza, Robert A., Friesel, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565826/ https://www.ncbi.nlm.nih.gov/pubmed/34714716 http://dx.doi.org/10.1080/21623945.2021.1987634 |
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