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Sprouty1 regulates gonadal white adipose tissue growth through a PDGFRα/β-Akt pathway

Expansion of visceral white adipose tissue (vWAT) occurs in response to nutrient excess, and is a risk factor for metabolic disease. SPRY1, a feedback inhibitor of receptor tyrosine kinase (RTK) signaling, is expressed in PDGFRa+ adipocyte progenitor cells (APC) in vivo. Global deficiency of Spry1 i...

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Detalles Bibliográficos
Autores principales: Yang, Xuehui, Pande, Shivangi, Koza, Robert A., Friesel, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565826/
https://www.ncbi.nlm.nih.gov/pubmed/34714716
http://dx.doi.org/10.1080/21623945.2021.1987634

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