Integrator enforces the fidelity of transcriptional termination at protein-coding genes

Integrator regulates the 3′-end processing and termination of multiple classes of noncoding RNAs. Depletion of INTS11, the catalytic subunit of Integrator, or ectopic expression of its catalytic dead enzyme impairs the 3′-end processing and termination of a set of protein-coding transcripts termed I...

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Detalles Bibliográficos
Autores principales: Dasilva, Lucas Ferreira, Blumenthal, Ezra, Beckedorff, Felipe, Cingaram, Pradeep Reddy, Gomes Dos Santos, Helena, Edupuganti, Raghu Ram, Zhang, Anda, Dokaneheifard, Sadat, Aoi, Yuki, Yue, Jingyin, Kirstein, Nina, Tayari, Mina Masoumeh, Shilatifard, Ali, Shiekhattar, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565846/
https://www.ncbi.nlm.nih.gov/pubmed/34730992
http://dx.doi.org/10.1126/sciadv.abe3393

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