Cargando…

Pan-Cancer Analysis of the N6-Methyladenosine Eraser FTO as a Potential Prognostic and Immunological Biomarker

BACKGROUND: Fat mass and obesity-associated protein (FTO) is a critical N6-methyladenosine (m6A) demethylase that participates in tumorigenesis and is associated with the prognosis of patients in some cancers. However, the key roles of FTO in pan-cancer are still largely obscure. METHODS: FTO expres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Chengwen, Liu, Yonghui, Ju, Shaoqing, Wang, Xudong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565892/ https://www.ncbi.nlm.nih.gov/pubmed/34744452 http://dx.doi.org/10.2147/IJGM.S331752

Ejemplares similares

Deregulation of N6-Methyladenosine RNA Modification and Its Erasers FTO/ALKBH5 among the Main Renal Cell Tumor Subtypes
por: Guimarães-Teixeira, Catarina, et al.
Publicado: (2021)

Understanding the roles of N(6)-methyladenosine writers, readers and erasers in breast cancer
por: Fang, Runping, et al.
Publicado: (2021)

Identification and Characterization of a Glucometabolic Prognostic Gene Signature in Neuroblastoma based on N6-methyladenosine Eraser ALKBH5
por: Tan, Kezhe, et al.
Publicado: (2022)

The potential role of RNA N6-methyladenosine in Cancer progression
por: Wang, Tianyi, et al.
Publicado: (2020)

Roles of N6‐Methyladenosine Demethylase FTO in Malignant Tumors Progression
por: Zheng, Qing-Kang, et al.
Publicado: (2021)

Predict Epitranscriptome Targets and Regulatory Functions of N(6)-Methyladenosine (m(6)A) Writers and Erasers
por: Song, Yiyou, et al.
Publicado: (2019)

Comprehensive Analysis of N6-Methyladenosine (m6A) Writers, Erasers, and Readers in Cervical Cancer
por: Condic, Mateja, et al.
Publicado: (2022)

Large tumor suppressor 2 is a prognostic biomarker and correlated with immune infiltrates in colorectal cancer
por: Zhao, Chengwen, et al.
Publicado: (2021)

Comprehensive immunohistochemical analysis of N6-methyladenosine (m6A) writers, erasers, and readers in endometrial cancer
por: Ralser, Damian J., et al.
Publicado: (2022)

N(6)-Methyladenosine in Nuclear RNA is a Major Substrate of the Obesity-Associated FTO
por: Jia, Guifang, et al.
Publicado: (2011)

The m(6)A eraser FTO facilitates proliferation and migration of human cervical cancer cells
por: Zou, Dongling, et al.
Publicado: (2019)

FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis
por: Zhao, Xu, et al.
Publicado: (2014)

N(6)-methyladenosine demethylases Alkbh5/Fto regulate cerebral ischemia-reperfusion injury
por: Xu, Kaiwei, et al.
Publicado: (2020)

Correction to: The m(6)A eraser FTO facilitates proliferation and migration of human cervical cancer cells
por: Zou, Dongling, et al.
Publicado: (2020)

Gene Polymorphisms of m6A Erasers FTO and ALKBH1 Associated with Susceptibility to Gastric Cancer
por: Li, Yue, et al.
Publicado: (2022)

The Potential Role of N6-Methyladenosine (m6A) Demethylase Fat Mass and Obesity-Associated Gene (FTO) in Human Cancers
por: Wang, Jin-yan, et al.
Publicado: (2020)

Nitric oxide inhibits FTO demethylase activity to regulate N(6)-methyladenosine mRNA methylation
por: Kuschman, Hannah Petraitis, et al.
Publicado: (2023)

N6-Methyladenosine-Regulated mRNAs: Potential Prognostic Biomarkers for Patients With Lung Adenocarcinoma
por: Sun, Junjun, et al.
Publicado: (2021)

Pan-Cancer Analysis of FURIN as a Potential Prognostic and Immunological Biomarker
por: Zhou, Bolun, et al.
Publicado: (2021)

N(6)-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5
por: Zou, Shui, et al.
Publicado: (2016)

AMPK regulates lipid accumulation in skeletal muscle cells through FTO-dependent demethylation of N(6)-methyladenosine
por: Wu, Weiche, et al.
Publicado: (2017)

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3
por: Niu, Yi, et al.
Publicado: (2019)

N6‐methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO‐PGC‐1α signalling axis
por: Zhuang, Changshui, et al.
Publicado: (2019)

Pan-Cancer Analysis Reveals FH as a Potential Prognostic and Immunological Biomarker in Lung Adenocarcinoma
por: Zhang, Heng, et al.
Publicado: (2021)

N6-Methyladenosine Methylation Regulator RBM15 is a Potential Prognostic Biomarker and Promotes Cell Proliferation in Pancreatic Adenocarcinoma
por: Zhao, Zhiying, et al.
Publicado: (2022)

GPC2 Is a Potential Diagnostic, Immunological, and Prognostic Biomarker in Pan-Cancer
por: Chen, Guoming, et al.
Publicado: (2022)

MCM10, a potential diagnostic, immunological, and prognostic biomarker in pan-cancer
por: Chen, Dengwang, et al.
Publicado: (2023)

LncRNA FTO-IT1 promotes glycolysis and progression of hepatocellular carcinoma through modulating FTO-mediated N6-methyladenosine modification on GLUT1 and PKM2
por: Wang, Fan, et al.
Publicado: (2023)

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing
por: Bartosovic, Marek, et al.
Publicado: (2017)

A fluorescent methylation-switchable probe for highly sensitive analysis of FTO N(6)-methyladenosine demethylase activity in cells
por: Cheong, Adeline, et al.
Publicado: (2018)

N6-methyladenosine demethylase FTO suppressed prostate cancer progression by maintaining CLIC4 mRNA stability
por: Zou, Libin, et al.
Publicado: (2022)

Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner
por: Wu, Yifei, et al.
Publicado: (2023)

Pan-cancer analysis of the prognostic and immunological role of ANLN: An onco-immunological biomarker
por: Liu, Kejun, et al.
Publicado: (2022)

N6-Methyladenosine-Related lncRNAs Are Potential Prognostic Biomarkers and Correlated With Tumor Immune Microenvironment in Osteosarcoma
por: Zheng, Di, et al.
Publicado: (2022)

N6-methyladenosine-related non-coding RNAs are potential prognostic and immunotherapeutic responsiveness biomarkers for bladder cancer
por: Lu, Miaolong, et al.
Publicado: (2021)

N6-methyladenosine-regulated ADIRF impairs lung adenocarcinoma metastasis and serves as a potential prognostic biomarker
por: Teng, Yin, et al.
Publicado: (2023)

FTO fuels diabetes-induced vascular endothelial dysfunction associated with inflammation by erasing m(6)A methylation of TNIP1
por: Zhou, Chuandi, et al.
Publicado: (2023)

Erase que erase -- : cuentos
por: Massieu, Cuca
Publicado: (1982)

PHF5A is a potential diagnostic, prognostic, and immunological biomarker in pan-cancer
por: Ding, Na, et al.
Publicado: (2023)

Clinical and immunological characteristics of TGM3 in pan-cancer: A potential prognostic biomarker
por: Zhang, Wenqing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ljcd2pprrkgs6ri6b6vd1vqs42